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In observance of US Thanksgiving holiday, Agilent Cross Lab iLab Operations Software will be closed during US hours on Thursday November 23rd and Friday November 24th, 2017. EU and APAC support coverage will remain open during this time. We will resume US support hours on Monday November 27th, 2017. For urgent matters, please add "URGENT" to the ticket subject and these requests will be prioritized first.

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Mass Spectrometry Resource

Overview of Services

 

Mission:
The NIH/NIGMS-supported Biomedical Mass Spectrometry Core provides service, collaboration, training and advice on mass spectrometry-based analysis of biomolecules involved in metabolism, nutrition, obesity, diabetes, cancer and other pathophysiologic conditions.

The Core supports extensive research programs and mass spectrometry platforms for routine and custom-designed analyses focused on characterizing, identifying and quantifying lipids, carbohydrates, peptides, amino acids, many metabolic intermediates, and stable isotope labeled biomolecules found in in vitro and in vivo models.

Goals:

  • Establish collaborative research projects with basic and applied investigators at Washington University and other Institutions
  • Provide mass spectrometry-based analytical services
  • Educate and train students/fellows/junior faculty in the use and applications of mass spectrometry
  • Disseminate our research findings and inform the community about biomedical mass spectrometry

 

Leadership

 

Director: John Turk, MD, PhD; Professor of Medicine
Assistant Director: Fong-Fu Hsu, PhD; Research Professor of Medicine
Assistant Director: Kevin Yarasheski, PhD; Professor of Medicine
Staff Scientists: Jan Crowley, Robert Chott, Alan Bohrer, Haowei Song, PhD
Engineer: Robert Sanders
Administrative: Susan Schumacher


Location and hours of operation

 

Hours

 

Location

 8am-5pm
Monday - Friday
or by appointment      

8th Floor SouthWest Tower,
Washington University Medical School,
St. Louis, MO 63110

Links and Resources

  1. What is Mass Spectrometry? http://player.vimeo.com/video/68728880
  2. Our Web-site: http://msr.dom.wustl.edu
  3. National Institutes of Health http://www.nih.gov/
  4. National Institute of General Medical Sciences http://www.nigms.nih.gov/
  5. Washington Univ. Department of Chemistry http://www.chemistry.wustl.edu/
  6. Washington Univ. Division of Metabolism, Endocrinology and Lipid Research http://endo.wustl.edu/
  7. Washington Univ. Proteomics Laboratory http://proteomics.wustl.edu

Contacts

Name Role Phone Email Location
Susan Schumacher
General Core administration
 
314 362-2602
 
sschumac@wustl.edu
 

 
Robert Sanders
MS Hardware & Software
 
314 362-8190
 
rsanders@wustl.edu
 

 
Jan Crowley
Metabolites
 
314 362-7878
 
jcrowley@wustl.edu
 

 
Fong-Fu Hsu, PhD
Complex lipids/lipidomics
 
314 362-0056
 
fhsu@wustl.edu
 

 
Kevin Yarasheski, PhD
Metabolomics
 
314 362-8173
 
key@wustl.edu
 

 
John Turk, MD, PhD
Executive decisions
 
314 362-8190
 
jturk@wustl.edu
 

 

Services

Name Description
Consultation 

Experimental design/planning, appropriate control samples, interpreting mass spectra, sample preparation, acquiring authentic biomolecules and heavy isotope-labeled internal standards

 
Endogenous receptor ligands   
GC-APCI-quadrupole-time of flight MS methods  

(e.g., vitamins)

 
Glycerolipids   
Identifying/characterizing unknown or novel biomolecules, compounds, drugs   
Lipidomic, metabolomic, peptidomic profiling  

(untargeted, comparative)

 
Most central carbon metabolic-lipid intermediates   
Peptides   
Phospholipids   
Polyols   
Post-translationally modified peptides and proteins   
Prokaryotic biomolecules 

(e.g., bacteria)

 
Prostanoids   
Protein, lipid or metabolite flux measures using heavy isotope-labeled precursors  

(in vitro or in vivo)

 
Short and long chain fatty acyls   
Specialized Services 

MS instrument repairs, maintenance

 
Sphingolipids   
Sterol lipids   
Synthetic molecule/compound   
Training 

Instrument operation,  data analysis-processing-software, sample preparation, library/database searches for identifying candidate biomolecules

 

Service List


Search available services: View: by category alphabetically
Custom Designed Sample Analyses (7)
Other (3)
Routine Sample Analyses (10)