Mission:
The NIH/NIGMS-supported Biomedical Mass Spectrometry Core provides service, collaboration, training and advice on mass spectrometry-based analysis of biomolecules involved in metabolism, nutrition, obesity, diabetes, cancer and other pathophysiologic conditions.
The Core supports extensive research programs and mass spectrometry platforms for routine and custom-designed analyses focused on characterizing, identifying and quantifying lipids, carbohydrates, peptides, amino acids, many metabolic intermediates, and stable isotope labeled biomolecules found in in vitro and in vivo models.
Goals:
Director: John Turk, MD, PhD; Professor of Medicine
Assistant Director: Fong-Fu Hsu, PhD; Research Professor of Medicine
Assistant Director: Kevin Yarasheski, PhD; Professor of Medicine
Staff Scientists: Jan Crowley, Robert Chott, Alan Bohrer, Haowei Song, PhD
Engineer: Robert Sanders
Administrative: Susan Schumacher
Hours |
Location |
8am-5pm |
8th Floor SouthWest Tower, |
Name | Role | Phone | Location | |
---|---|---|---|---|
Susan Schumacher |
General Core administration
|
314 362-2602
|
sschumac@wustl.edu
|
|
Robert Sanders |
MS Hardware & Software
|
314 362-8190
|
rsanders@wustl.edu
|
|
Jan Crowley |
Metabolites
|
314 362-7878
|
jcrowley@wustl.edu
|
|
Fong-Fu Hsu, PhD |
Complex lipids/lipidomics
|
314 362-0056
|
fhsu@wustl.edu
|
|
Kevin Yarasheski, PhD |
Metabolomics
|
314 362-8173
|
key@wustl.edu
|
|
John Turk, MD, PhD |
Executive decisions
|
314 362-8190
|
jturk@wustl.edu
|
Service List |
► Custom Designed Sample Analyses (7) | |||
Name | Description | Price | |
---|---|---|---|
Endogenous receptor ligands | Inquire | ||
GC-APCI-quadrupole-time of flight MS methods |
(e.g., vitamins) |
Inquire | |
Identifying/characterizing unknown or novel biomolecules, compounds, drugs | Inquire | ||
Lipidomic, metabolomic, peptidomic profiling |
(untargeted, comparative) |
Inquire | |
Post-translationally modified peptides and proteins | Inquire | ||
Prokaryotic biomolecules |
(e.g., bacteria) |
Inquire | |
Protein, lipid or metabolite flux measures using heavy isotope-labeled precursors |
(in vitro or in vivo) |
Inquire | |
► Other (3) | |||
Name | Description | Price | |
Consultation |
Experimental design/planning, appropriate control samples, interpreting mass spectra, sample preparation, acquiring authentic biomolecules and heavy isotope-labeled internal standards |
Inquire | |
Specialized Services |
MS instrument repairs, maintenance |
Inquire | |
Training |
Instrument operation, data analysis-processing-software, sample preparation, library/database searches for identifying candidate biomolecules |
Inquire | |
► Routine Sample Analyses (10) | |||
Name | Description | Price | |
Glycerolipids | Inquire | ||
Most central carbon metabolic-lipid intermediates | Inquire | ||
Peptides | Inquire | ||
Phospholipids | Inquire | ||
Polyols | Inquire | ||
Prostanoids | Inquire | ||
Short and long chain fatty acyls | Inquire | ||
Sphingolipids | Inquire | ||
Sterol lipids | Inquire | ||
Synthetic molecule/compound | Inquire |